SANJAY ASTHANA

Contact Information

Photo of SANJAY ASTHANA
SANJAY ASTHANA

PROFESSOR

2870 UNIVERSITY AVE
SUITE 106
MADISON, WI 53705
Mail Code: 9095

(608) 263-9969




Biography

Current Appointments

Duncan G. and Lottie H. Ballantine Chair in Geriatrics
Head, Section of Geriatrics and Gerontology
Department of Medicine
University of Wisconsin School of Medicine
Madison, WI 53705 U.S.A.

Director
Geriatric Research, Education and Clinical Center (GRECC)
William S. Middleton Memorial Veterans Hospital
Madison, WI 53705 U.S.A.

Director
Memory Research Program
University of Wisconsin School of Medicine and Public Health
William S. Middleton Memorial Veterans Hospital
Madison, WI 53705 U.S.A

Associate Director
Wisconsin Alzheimer's Institute
University of Wisconsin-Madison School of Medicine and Public Health
Madison, WI 53705 U.S.A.

Education

GRADUATE

July 1973 - March 1978 University College of Medical Sciences
University of Delhi, New Delhi, India
April 1980 MB; BS

RESIDENCY

July 1987 - June 1988 Third year Senior Resident, Department of Medicine
University of Saskatchewan School of Medicine
Saskatoon, Canada S7N-OXO.
July 1988 - June 1989 Chief Resident (4th year)
Department of Internal Medicine
University of Saskatchewan School of Medicine
Saskatoon, Canada S7N-OXO.

FELLOWSHIPS

August 1989 - June 1992 Clinical Research Fellow
Division of Geriatric Medicine and Gerontology
The Johns Hopkins University School of Medicine
Baltimore, MD 21224, U.S.A.
February 1990 - Sep. 1990 Guest Researcher
Laboratory of Neurosciences
National Institute on Aging
National Institutes of Health (NIH)
Bethesda, MD 20892, U.S.A.
October 1990 - Sep. 1992 Fogarty Staff Fellow
Laboratory of Neurosciences
National Institute on Aging, NIH
Bethesda, MD 20892, U.S.A.
September 1992 - July 1993 Senior Staff Fellow
Laboratory of Neurosciences
National Institute on Aging, NIH
Bethesda, MD 20892, U.S.A.

Research Interests

Clinical psychopharmacology and neuroendocrinology of gonadal steroids and cholinergic drugs in Alzheimer's disease and healthy aging

  1. Cognitive and neuroendocrine effects of estrogen and testosterone administration in Alzheimer's disease and healthy aging.
  2. Potential beneficial effects of estrogen and testosterone treatment on performance-based measures of independent living skills for healthy older adults as well as those with Alzheimer's disease.
  3. Identification of biological markers for therapeutic responsivity to estrogen for women with Alzheimer's disease.
  4. Evaluation of therapeutic efficacy of raloxifene, a selective estrogen receptor modulator (SERM), in subjects with Alzheimer's disease.
  5. Cholinergic drugs: Clinical psychopharmacology studies in Alzheimer's disease.
  6. Clinical pharmacokinetics and neuroendocrinology of cholinergic drugs in subjects with AD.

Search for Sanjay Asthana's literature abstracts on PubMed

SELECTED PUBLICATIONS
Asthana S, Craft S, Baker LD, Raskind MA, Avery E, Lofgreen C, Veith RC, Plymate SR: Cognitive and neuroendocrine response to transdermal estrogen in women with Alzheimer's disease: results of a randomized, placebo-controlled pilot study. Psychoneuroendocrinology, vol 24(6), pp 657-678, 1999.

Craft S, Asthana S, Schellenberg G, Cherrier M, Baker LD, Newcomer J, Plymate SR, Latendresse S, Petrova A, Raskind MA, Peshkind E: Insulin metabolism in Alzheimer's disease differs according to apolipoprotein E genotype. Neuroendocrinology, vol 295, pp 2750-2757, 1999.

Craft S, Asthana S, Newcomer JW, Wilkinson CW, Baker LD, Cherrier M, Tio-Mattis, I, Lofgreen C, Latendresse S, Petrova A, Plymate SR, Raskind MA, Grimwood K, Vieth RC: Enhancement of memory in Alzheimer's disease with insulin and somatostatin, but not glucose, Arch Gen Psychiatry, vol 56, pp 1135-1140, 1999.

Craft S, Asthana S, Schellenberg G, Baker LD, Cherrier M, Boyt AA, Martins RN, Raskind MA, Peshkind E, Plymate S: Insulin effects on glucose metabolism, memory, and plasma amyloid precursor protein in Alzheimer's disease differ according to apolipoprotein-E genotype. Annals N Y Acad Sci, vol 903, pp 222-228, 2000.

Asthana S, Baker LD, Craft S, Stanczyk FZ, Veith RC, Raskind MA, Plymate SR: High-dose estradiol improves cognition for women with Alzheimer's disease: Results of a randomized study. Neurology, vol 57, pp 605-612, 2001.

Cherrier M, Craft S, Asthana S, Plymate S, Baker LD, Matsumoto AM, Peskind E, Raskind MA, Brodkin K, Bremner WM, Petrova A, LaTendresse S: Effects of exogenous testosterone administration on spatial and verbal memory in healthy older men: A randomized, double-blind, placebo-controlled study. Neurology, vol 57, pp 80-88, 2001.

Work Related Links

None Provided

Associated Staff

None Provided