Department of Medicine
University of Wisconsin
MATTHEW R WOLFF
Contact Information
600 HIGHLAND AVE
MADISON, WI 53792
Mail Code: 3248
Biography
Chief, Division of Cardiovascular Medicine
Tuchman Professor of Cardiology
Matthew Wolff graduated from the Johns Hopkins University School of Medicine and received his internal medicine training at Johns Hopkins Hospital. From 1988-1989 he served as an assistant chief of service in the Department of Medicine at Hopkins, then remained to complete both cardiology and interventional cardiology fellowships. He joined the faculty at the University of Wisconsin Medical School in 1993 and in July of 1999 became the Director of the Adult Cardiac Catheterization Laboratory. In 2005 he became Chief of the Division of Cardiovascular Medicine.
In addition to his clinical activities as an interventional cardiologist, Wolff has maintained both clinical and basic cardiovascular research programs. He has been the principal investigator in a number of multicenter trials in interventional cardiology.
His research interests include interventional cardiology, cardiac gene transfer and therapeutic angiogenesis and has resulted in more than 40 original, peer-reviewed publications in major cardiovascular journals. He is a former recipient of a National Institutes of Health Clinical Investigator Development Award, and currently is the chair of the Small Business Special Emphasis Panel of the National Heart, Lung and Blood Institute.
Dr. Wolff is currently the Governor of the Wisconsin Chapter of the American College of Cardiology and serves on the ACCs National Interventional Council and the ACC Innovations in Intervention program committee. He was a co-chair of the ACCs 2006 Annual National Scientific Sessions.
Dr. Wolff maintains an active inpatient and outpatient clinical practice specializing in ischemic heart disease.
Search for Matthew Wolff's literature abstracts on PubMed
Wolff MR, McDonald KS, Moss RL. Rate of tension development in cardiac muscle varies with level of activator calcium. Circ Res 1995; 76:154-160.
Wolff MR, Whitesell LF, Moss RL. Calcium sensitivity of isometric tension is increased in experimental heart failure. Circ Res 1995; 76:781-789.
Wolff MR, Buck SH, Stoker SW, Greaser ML, Mentzer RM. Myofibrillar calcium sensitivity of isometric tension is increased in human dilated cardiomyopathies: Role of altered beta-adrenergically mediated protein phosphorylation. J Clin Invest 1996; 98:167-176.
McDonald KS, Wolff MR, Moss RL. Force-velocity and power-load curves in rat skinned cardiac myocytes. J Physiol 1998; 511:519-531.
Fatkin D, MacRae C, Sasaki T, Wolff MR, Porcu M, Frenneaux M, Atherton J, Vidaillet HJ, Spudich S, De Girolami U, Seidman JG, Seidman CE. Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease. New Engl J Med 1999; 341:1715-1724.